The price of a drug should be based on its therapeutic benefits – not just what the market will bear

The U.S. pharmaceutical industry has innovated in response to the pandemic, providing not only vaccines but also therapies to treat people with COVID-19. But an outdated law designed to spur development of lifesaving drugs risks making new treatments—for COVID-19 as well as other diseases—unaffordable for many Americans. Many pharmaceutical companies rely on the Orphan Drug […]

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What is the probability of receiving a correct diagnosis of depression?

Three previous meta-analyses reported that, compared to the Structured Clinical Interview for the DSM (SCID), alternative reference standards, primarily the Composite International Diagnostic Interview (CIDI) and the Mini International Neuropsychiatric Interview (MINI), tended to misclassify major depression status, when controlling for depression symptom severity. However, there was an important lack of precision in the results. […]

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